Center for Selective C–H Functionalization
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An expedient synthesis of maraviroc (UK-427,857) via C–H functionalization

Bedell, T. Aaron Graham Hone Justin Du Bois Erik Sorensen

Published in Tetrahedron Letters

A new, concise synthesis of the CCR-5 receptor antagonist maraviroc (UK-427,857) from 3-phenyl-1-propanol has been completed in four steps featuring a site-selective C–H functionalization.

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