Syntheses of Isoquinoline and Substituted Quinolines in Charged Microdroplets
Published in Angewandte Chemie International Edition in English
Mechanistic analysis of an asymmetric palladium-catalyzed conjugate addition of arylboronic acids to ß-substituted cycli...
Published in Advances in Chemical Engineering and Science
Palladium(II)-Catalyzed Allylic C–H Oxidation of Hindered Substrates Featuring Tunable Selectivity Over Extent of Oxidat...
Published in Angewandte Chemie International Edition in English
Pyridine N-Oxide vs Pyridine Substrates for Rh(III)-Catalyzed Oxidative C–H Bond Functionalization
Published in Journal of the American Chemical Society
Factors Impacting the Mechanism of the Mono-N-Protected Amino Acid Ligand-Assisted and Directing-Group-Mediated Pd-Catal...
Published in ACS Catalysis
Acceleration of reaction in charged microdroplets
Published in Quarterly Reviews of Biophysics
Highly Active Nickel Catalysts for C–H Functionalization Identified through Analysis of Off-Cycle Intermediates
Published in Journal of the American Chemical Society
Fundamental Aspects of the Metal-Catalyzed C–H Bond Functionalization by Diazocarbenes
Published in Understanding Organometallic Reaction Mechanisms and Catalysis
Vicinal diamination of alkenes under Rh-catalysis.
Published in Journal of the American Chemical Society
The synthesis of 1,2-diamines has been achieved through a single-step, tandem sequence involving Rh-catalyzed aziridination followed by NaI-promoted rearrangement to an isomeric cyclic sulfamide. Facile ring opening of these products in hot water and pyridine affords differentially protected vicinal diamines. Demonstration of the utility of this me...
Pd(II)-Catalyzed meta-C–H Olefination, Arylation, and Acetoxylation of Indolines Using a U-Shaped Template
Published in Journal of the American Chemical Society
meta-C-H olefination, arylation, and acetoxylation of indolines have been developed using nitrile-containing templates. The combination of a monoprotected amino acid ligand and the nitrile template attached at the indolinyl nitrogen via a sulfonamide linkage is crucial for the meta-selective C-H functionalization of electron-rich indolines that are...
